Does Working Out Result in T Cell Mitochondrial Gains?

The positive effects of aerobic exercise training on skeletal muscle metabolism are well recognized. Exercise also leads to beneficial metabolic adaptations in other organs, including the brain, liver, kidneys and adipose tissue. However, the effects of exercise on immune cell metabolism are largely unknown. Immune cells that circulate throughout the body are exposed to exercise-associated […]

Vertical Loading Rate Should Not Be Used as a Predictor of Running Injury

Running is a popular form of exercise due to its health benefits and low economic cost; however, the prevalence of running-related injuries is on the rise. With most running injuries classified as overuse injuries due to excessive, repetitive loading, clinicians and researchers are looking to develop measures of this loading to assess a runner’s injury […]

Meeting the 50th Percentile for 24-hour Movement Helps Cognitive Function

Alzheimer’s disease and related dementias are debilitating conditions leading to impaired cognitive processes and worsening physical functioning. They place significant burden on caregivers and health care systems. Roughly 15 million cases of cognitive impairment and Alzheimer’s disease in the U.S. are projected by 2060. While there are no medical treatments to delay Alzheimer’s disease progression, […]

Computational Neuroscience Approaches to Exercise Behaviors in Older Adults

Engagement in physical exercise has shown widespread benefits on cardiovascular, physical, emotional and cognitive health in older adults. However, initiating and sustaining an exercise routine over the long term (e.g., six months or more) is incredibly challenging. Our historical understanding of the factors that determine engagement in physical exercise comes from psychological and psychosocial theories, […]

Cancer Survivors with Chronic Fatigue Display Rapid Impairments in Muscle Function During Exercise

Cancer-related fatigue (C-rF) is a debilitating symptom that affects around one-third of people for months or years after cancer treatment. While the etiology of C-rF remains uncertain, it has been demonstrated that cancer survivors with C-rF display impaired exercise tolerance compared with those without C-rF, with the degree of exercise intolerance associated with chronic fatigue […]

Cardiac Adaptation to Endurance and Resistance Training

In our Studies of Twin Responses to Understand Exercise THerapy (STRUETH) trial, we recruited monozygotic and dizygotic twin pairs and supervised them through three months of endurance training and three months of resistance exercise training. Each twin pair exercised together, at matched exercise prescriptions, and all subjects undertook both forms of exercise. We measured many […]

Racial, Ethnic, and Nativity-Based Differences in Physical Activity Behaviors

As exercise professionals ranging from clinicians to personal trainers to researchers, we know that most adults in the United States are not getting enough moderate-to-vigorous intensity aerobic physical activity (MVPA). It is important for us to understand who may be at especially high risk of physical inactivity. Prior studies have shown that there may be […]

Q&A with New ACSM President Stacy Fischer

Anastasia “Stacy” Fischer, M.D., FACSM, was installed as president of ACSM during last month’s annual meeting in San Diego. SMB editor Lenny Kaminsky, Ph.D., FACSM, asked Dr. Fischer several questions that may be of interest to ACSM members. We appreciate Dr. Fischer taking the time to provide the following answers. Q: What can you say about ACSM’s annual meeting, the […]

Reconsidering the Importance of Cardiorespiratory Fitness in Early Adulthood

Cardiorespiratory fitness reflects integration of several body systems, including the cardiovascular, respiratory and musculoskeletal systems. It helps optimize heart health and is an important predictor of adverse health outcomes, including premature death, heart attack and heart disease. Indeed, the American Heart Association suggests that cardiorespiratory fitness should be measured as a vital sign during a doctor’s visit. […]

Air Pollution Diminishes the Benefits of Physical Activity for Brain Health

Physical activity is recognized as one of the key healthy lifestyle behaviors that reduces the risk of developing dementia late in life. Physical activity requires increased rates of respiration. Thus, in areas with high levels of air pollution, physical activity may increase exposure to particulate matter and gases that are linked with higher risk of […]